STOP-D
Sertraline TO prevent Post-TBI Depression
What is
STOP-D?
The STOP-D study is a clinical trial. We want to find out if a commonly used antidepressant, called sertraline, is better at preventing depression than a placebo (also called a dummy or 'fake' pill). We will also want to study if sertraline improves quality of life, improve other symptoms like headaches, irritability, memory loss.
Why is
STOP-D?
Traumatic brain injury (TBI) is a disruption in the normal function of the brain caused by an external force. It is one of the most common presentations in Accident and Emergency (A&E) departments, especially in young males and older people. The prevalence rates of post TBI depression (PTD) is on average 10 times higher than the general population, and this risk emerges very soon after the injury.
5%
of the general population have some form of depression
50%
of people with a head injury will have some form of depression over the next 10 years
...had a Traumatic Brain Injury in the last 8 Weeks?
...been to A&E as a result of your injury?
